Heterogeneity in Statistical Genetics: How to Assess, Address, and Account for Mixtures in Association Studies free ebook download.

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Heterogeneity in Statistical Genetics: How to Assess, Address, and Account for Mixtures in Association Studies free ebook download

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Biology

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Catalogue

Author(s):	Derek Gordon

Date:	2020	Format:	PDF,EPUB	Language:	English	ISBN/ASIN:	3030611205
Pages:	1	OCR:		Quality:		ISBN13:
Uploader:	risotor	Upload Date:	12/17/2020 10:34:41 AM

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Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.
In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.

We anticipate that this book will be useful to researchers who want to estimate heterogeneity in their data, develop or apply genetic association statistics where heterogeneity exists, and accurately evaluate statistical power and sample size for genetic association through the application of robust experimental design.
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Links Table

	Title	Link	Password	Size (MB)	Thank to	Inform Admin
2919261	Book	https://florenfile.com/6ypwvdaoeui8...		6.22	risotor
2919262	Book	https://florenfile.com/90jg0htu7l99...		22.24	risotor

Tags: Account Address Assess Association Genetics Heterogeneity Mixtures Statistical Studies

Title	Link	Password	Size	Reason

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