Preclinical Development Handbook: Toxicology free ebook download.

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Preclinical Development Handbook: Toxicology free ebook download

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Medicine

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Catalogue

Author(s):	Shayne Cox Gad

Date:	2008	Format:	pdf	Language:	English	ISBN/ASIN:	0470248467
Pages:	1	OCR:		Quality:		ISBN13:
Uploader:	tvladb77	Upload Date:	2/12/2021 11:59:04 PM

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A clear, straightforward resource to guide you through preclinicaldrug development

Following this book's step-by-step guidance, you can successfullyinitiate and complete critical phases of preclinical drugdevelopment. The book serves as a basic,comprehensive reference toprioritizing and optimizing leads, toxicity, pharmacogenomics,modeling, and regulations. This single definitive, easy-to-useresource discusses all the issues that need consideration andprovides detailed instructions for current methods andtechniques.

Each chapter was written by one or more leading experts in thefield. These authors, representing the many disciplines involved inpreclinical toxicology screening and testing, give you the toolsneeded to apply an effective multidisciplinary approach. Theeditor, with more than thirty years' experience working withpharmaceutical and biotechnology companies, carefully reviewed allthe chapters to ensure that each one is thorough, accurate, andclear.

Among the key topics covered are:
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In vitro mammalian cytogenetics tests
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Phototoxicity
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Carcinogenicity studies
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The pharmacogenomics of personalized medicine
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Bridging studies
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Toxicogenomics and toxicoproteomics

Each chapter offers a full exploration of problems that may beencountered and their solutions. The authors also set forth thelimitations of various methods and techniques used in determiningthe safety and efficacy of a drug during the preclinicalstage.

This is a hands-on guide for pharmaceutical scientists involved inpreclinical testing,enabling them to perform and documentpreclinical safety tests to meet all FDA requirements beforeclinical trials may begin.

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Tags: Development Handbook Preclinical Toxicology

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