Lysosomal Storage Diseases: Pathobiology and Therapeutic Consideration free ebook download.

Home : Book details

Lysosomal Storage Diseases: Pathobiology and Therapeutic Consideration free ebook download

Category:
Medicine

Views: 257
Likes: 268

Catalogue

Author(s):	Lysosomal Storage Diseases :

Date:	2016-04-20	Format:	PDF	Language:	English	ISBN/ASIN:	1634846613
Pages:	130	OCR:		Quality:		ISBN13:	9781634846615
Uploader:	alex21s	Upload Date:	6/17/2018 11:07:52 AM

To download click on link in the Links Table below

Description: Click to see full description

In the current publication, the aim will be to summarize the latest findings regarding the consequences of lysosomal dysfunction, which occur primarily because of a disruption in the sequential degradation of various substrates generated by cellular turnover. Prior to delving into deleterious cellular events, the nature and physiology of the lysosome will be reviewed.

Several mechanisms of disease have been described  although seemingly discrete and initially involving different subcellular compartments (e.g., autophagosome and the lysosome), these events are interconnected. Moreover, even when a particular defect is identified (e.g., impairment of mitophagy), the observed changes may be mediated by distinctive processes  which calls attention to myriad ways cells can respond to injury. In each of the relevant sections, disease-specific observations are described.

Topics covered in the book are grouped into three sections: (1) physiologic events involving or occurring within the confines of the lysosome  (2) cellular perturbations implicated in lysosomal storage disease  and (3) therapeutic strategies and views relating to genetic screening and counselling. Background material and additional information are provided in boxed sections at the end of each chapter. Diagrams are included to facilitate greater understanding of relevant themes. The subject matters that are discussed can be found scattered over several publications  the current monograph attempts to collate several perspectives into a coherent narrative and serve as a convenient resource.

Links Table

	Title	Link	Password	Size (MB)	Thank to	Inform Admin
2196392	Book	http://tezfiles.com/file/74a1eea1c14b7...		2.56	alex21s

Tags: Consideration Diseases Lysosomal Pathobiology Storage Therapeutic

Title	Link	Password	Size	Reason

Those who downloaded this book also downloaded the following books:
Comments

New comment: