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Directed Molecular Evolution of Proteins: Or How to Improve Enzymes for Biocatalysis free ebook download

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Biology

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Author(s):	Susanne Brakmann

Date:	2002	Format:	pdf	Language:	English	ISBN/ASIN:	3527304231
Pages:	1	OCR:		Quality:		ISBN13:
Uploader:	tvladb77	Upload Date:	2/27/2021 8:21:13 PM

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Natural selection created optimal catalysts. However, optimal performance of enzyme catalysis does not necessarily refer to maximum reaction rate. Rather, it may be a compromise between specificity, rate, stability, and other chemical constraints that makes enzymes capable of catalyzing reactions under mild conditions and with high substrate specificity, accompanied by high regio- and enantioselectivity.
The book presented here focuses on the directed evolution of proteins, which has established itself as a powerful method for designing enzymes showing new substrate specificities. It includes a comprehensive repertoire of techniques for producing combinatorial enzyme libraries, while the functional gene expression in a suitable host helps in selecting the appropriate structure, making fast screening a necessity. This book illustrates both the theoretical background as well as the potential of this interesting method in practice - which is becoming ever more important even in classical organic synthesis!

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Tags: Biocatalysis Directed Enzymes Evolution Improve Molecular Proteins

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Directed Molecular Evolution of Proteins: Or How to Improve Enzymes for Biocatalysis free ebook download

Category: Biology

Description: Click to see full description

Category:
Biology