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Sex Hormones, Second Edition
This book provides a systematic and updated overview of the male/female sex-hormones and their impact in the biology and physiology of various organs. The book discusses their positive and negative association with the pathophysiology of various diseases (e.g. osteoporosis, cardiovascular-disease, hypogonadism, reproduction, cancer) and their therapeutic potential. Sex Hormones not only regulate reproductive function, but they also play a prominent role in the biology and physiology of several organs/tissues and in the pathophysiology of several diseases. During the last two decades, the information on the mechanisms of action of sex hormones, such as estrogens and androgens, has rapidly evolved from the conventional nuclear receptor dependent mechanisms to include additional non-nuclear, non-genomic and receptor-independent mechanisms. This highlights the need to update the current knowledge on sex hormones and their mode of action. Increasing evidence that exogenous/epigenetic factors can influence sex hormone production and action highlights the need to update our knowledge on the mechanisms involved. Contents Preface 1 Sex Hormones and Vascular Function 2 The Role of Sex Hormones in the Cardiovascular System 3 Serum Free Testosterone and Estradiol Levels in Perceptual-Verba I and Spatial Abilities Differences in Sex and Hand Preference 4 Sex Hormones and Infertility 5 Progesterone in Human Pregnancy and Parturition 6 Late - Onset Hypogonadism - New Point of View 7 Hypogonadism After Childhood Cancer Treatment 8 Osteoporsis in Men - A Crucial Role of Sex Hormones 9 Testosterone Deficiency Linked to Lower Urinary Tract Symptoms 10 Sex Hormones and Bacterial Infections 11 The Special Implication of Sex Hormones on Dendritic Cells During Pregnancy 12 Sex Hormones and Neuromuscular Control System 13 Acute and Chronic Testosterone Responses to Physical Exercise and Training 14 Hand Grip Strength in Relation to Morphological Measures of Masculinity, Fluctuating Asymmetry and Sexual Behaviour in Males And Females 15 Sex Differences in the Developmental Programming of Adult Disease 16 WW Domain-Containing Oxidoreductase is a Potential Receptor for Sex Steroid Hormones 17 Sex Steroids in Insects and the Role of the Endosymbiont Wolbachia: A New Perspective 18 Tissue-Specific Regulation of Sex Hormone Biosynthesis and Metabolism: Novel Aspects on Hormonal Signalling and Maintenance of Cellular Steroid Levels 19 Solid State and Thermal Behavior of 17b-Estradiol in Ammonioethyl Methacrylate Ester Copolymer