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Description of  Protein-Protein Interactions: A Molecular Cloning Manual, Second Edition

This is an updated edition of a manual that provides a thorough collection of the technical and theoretical issues involved in the study of protein associations, including standard methods, biophysical approaches, and, in a final section, a collection of computational methods for integrating and analyzing interactions. Summary: Revised, Updated, Expanded Second Edition Rating: 5 This second edition is much changed from the first edition of 2002. Most of the chapters in the earlier have been either extensively revised and brought up to date or replaced with new chapters (the old chapters are still available on a special web site). The format of the book is the same with forty-six chapters written by the leading researchers in the field. The chapters are grouped into sections as follows: 1. Protein-Protein Interactions in Biological Context 2. Standard Technologies to Probe Protein Interactions 3. Biophysical Approaches to Probe Protein Interactions 4. Novel High-Throughput Approaches to Probe Protein Interactions 5. Interactions of Proteins and Peptides 6. InVivo Imaging of Protein Interactions 7. Genome-wide and Computer-based Analysis of Protein Interactions 8. Design of Novel Interactions and Inhibitors in Drug Discovery This book is a summary of the state of the art in the field and is significantly improved over the first edition.