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Beyond Our Genes: Pathophysiology of Gene and Environment Interaction and Epigenetic Inheritance
3030352129 rar 3030352129 rar 3030352129 rar The genotype/phenotype dichotomy is being slowly replaced by a more complex relationship whereby the majority of phenotypes arise from interactions between ones genotype and the environment in which one lives. Interestingly, it seems that not only our lives, but also our ancestors lives, determine how we look. This newly recognized form of inheritance is known as (epi)genetic, as it involves an additional layer of information on top of the one encoded by the genes. Its discovery has constituted one of the biggest paradigm shifts in biology in recent years. Understanding epigenetic factors may help explain the pathogenesis of several complex human diseases (such as diabetes, obesity and cancer) and provide alternative paths for disease prevention, management and therapy. Read more