Tumor Suppressor Par-4: Structural Features, Molecular Mechanisms and Function free ebook download.

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Tumor Suppressor Par-4: Structural Features, Molecular Mechanisms and Function free ebook download

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Medicine

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Author(s):	no autor

Date:	2021	Format:	pdf	Language:	English	ISBN/ASIN:	3030735710
Pages:	333	OCR:		Quality:		ISBN13:
Uploader:	risotor	Upload Date:	1/30/2022 9:14:57 PM

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Par-4 is a tumor suppressor protein first discovered and identified in 1993 by Dr. Vivek Rangnekars laboratory in prostate cancer cells undergoing apoptosis.  Par-4 (later also known as PAWR) is a naturally occurring tumor suppressor. Studies have indicated that Par-4 selectively induces apoptosis in cancer cells while leaving normal, healthy, cells unaffected. Mechanisms contributing to the cancer-selective action of Par-4 have been associated with protein kinase A activation of intracellular Par-4 in cancer cells or GRP78 expression primarily on the surface of cancer cells. Par-4 is downregulated, inactivated or mutated in diverse cancers. This first of two volumes will be the first on the market on the topic of Par-4, and will provide the opportunity for researchers to discuss the future direction of studies, broaden the scope of research, and contribute a more complete understanding of the molecules structural features, key functional domains, regulation and relevant basic and clinical/translational facets.
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	Title	Link	Password	Size (MB)	Thank to	Inform Admin
3083705	Book	https://florenfile.com/v62egzm1d28o/3030...		0.00	risotor

Tags: Features Function Mechanisms Molecular Structural Suppressor Tumor

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